Electron tomography at 2.4-angstrom resolution : Nature : Nature Publishing Group

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URL

http://www.nature.com/nature/journal/v483/n7390/full/nature10934.html#/ref6

Description

Transmission electron microscopy is a powerful imaging tool that has found broad application in materials science, nanoscience and biology1, 2, 3. With the introduction of aberration-corrected electron lenses, both the spatial resolution and the image quality in transmission electron microscopy have been significantly improved4, 5 and resolution below 0.5 ångströms has been demonstrated6. To reveal the three-dimensional (3D) structure of thin samples, electron tomography is the method of choice7, 8, 9, 10, 11, with cubic-nanometre resolution currently achievable10, 11. Discrete tomography has recently been used to generate a 3D atomic reconstruction of a silver nanoparticle two to three nanometres in diameter12, but this statistical method assumes prior knowledge of the particle’s lattice structure and requires that the atoms fit rigidly on that lattice

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