Multimodal Nonlinear Microscopy: Histopathology of Brain Tumors

URL

http://www.laboratory-journal.com/science/medicine-diagnostics/multimodal-nonlinear-microscopy-histopathology-brain-tumors

Description

y combining three nonlinear microscopic imaging techniques to a multimodal microscopy approach, similar information on the morphology and chemical composition of unprocessed tissue can be extracted. Much greater depth penetration can be achieved in comparison to conventional light microscopy. This all-optical approach fuses coherent anti-Stokes Raman scattering (CARS), second-harmonic generation (SHG) and two-photon excited fluorescence (TPEF) imaging into a single microscopic setup.